ISRO Human Space Flight Centre (HSFC) Scientist/Engineer 'SD' PhD Recruitment 2026 — 6 Posts

The Human Space Flight Centre (HSFC), Bengaluru — the lead centre within the Indian Space Research Organisation (ISRO), Department of Space, Government of India for India's Human Space Flight Programme — has invited online applications for direct recruitment to 6 posts of Scientist/Engineer 'SD' in Level-11 of the Pay Matrix, vide Advertisement No. HSFC:01:RMT:2026 dated 10.08.2026. HSFC is undertaking multi-disciplinary R&D in new domains of human science and technology, with a focus on Bioastronautics, Human Space Sciences, and Space Habitat Systems. These are PhD-level Group 'A' posts across biomedical, biological, and computational-biology disciplines, selected purely through personal interview — there is no written examination in this recruitment process.

📋 Key Details at a Glance

🧬 Post Code-Wise Vacancy, Discipline & Qualification Details

All 6 posts require a Ph.D. in the specified discipline from a recognized university/institute as the essential qualification, along with a pre-requisite Master's + Bachelor's (or BS-MS dual degree) qualification chain. Reproduced below in full, post code by post code.

Post Code 01 — Bioinstrumentation / Biophysics / Medical Physics (1 post, UR)

Post Code 02 — Developmental Biology / Biotechnology (1 post, UR)

Post Code 03 — Cellular & Molecular Biology / Cell Biology (1 post, UR)

Post Code 04 — Computational Biology / Systems Biology / Bioinformatics (1 post, UR)

Post Code 05 — Biomedical Engineering / Biomedical Sciences (Biomechanics) (1 post, UR)

Post Code 06 — Biomedical Engineering / Biomedical Sciences (Bio-Imaging/Signal Processing) (1 post, UR)

📝 Qualification Notes (Applicable to All 6 Posts)

• Only candidates possessing the required qualification as on the last date of application (30.08.2026) are eligible to apply.
• Candidates holding degrees from foreign universities must produce an equivalency certificate issued by the Association of Indian Universities (AIU), New Delhi, at the time of Personal Interview.
• The ME/M.Tech/MS/M.Sc./BE/B.Tech/BSc/BS-MS qualification for each post must have been completed within the stipulated duration of the course as prescribed by the university.
• Candidates who completed a professional course through Open and Distance Learning (ODL) are not eligible.
• Where a university's degree certificate/mark-sheet states both CGPA and percentage, at least one of the two must meet ISRO's eligibility norms.
• Where only CGPA (or only percentage) is stated, that figure must independently meet ISRO's eligibility criteria — conversion between CGPA and percentage is not permitted, regardless of any conversion formula prescribed by the university. Rounding-off of marks is also not allowed.
• For dual/integrated degrees: if CGPA/percentage for graduation and post-graduation are listed separately, each is reckoned separately; if only a single combined CGPA/percentage is listed for the whole course, that figure is used; if the university prescribes none, the cumulative CGPA/percentage from the final/consolidated mark-sheet is used.

🛰️ Job Requirements — Post Code Wise

The job requirement below is an outline of the work profile only, and is not exhaustive, as stated in the notification.

Post Code 01

• Design and validate wearable health monitoring sensors and systems, and instrumentation of biomedical sensors.
• Bio-signal data acquisition and processing.
• Medical imaging and informatics.
• Development of portable diagnostic devices and wearable sensors.

Post Code 02

• Radiation biology and exposure models.
• Develop regenerative approaches to preserve musculoskeletal integrity during training and in space.
• Mammalian and stem cell culture; primary cell lines; 3D/organoid culture systems.
• In vivo and ex vivo animal physiological studies.
• Working on disease biology models relevant to astronaut health.
• Host-pathogen interaction studies under stress/microgravity.

Post Code 03

• Study immune and cellular adaptation across the astronaut health cycle.
• Bioinformatics analysis of proteomic data for biomarker identification for spaceflight application.
• Molecular cloning, confocal microscopy, live-cell imaging, gene editing, for spaceflight application.
• Large-scale proteomic dataset analysis, gene expression, and statistical workflows.

Post Code 04

• In-silico models to anticipate astronaut adaptation, assess countermeasures, and guide rehabilitation.
• Development of therapeutics and space-grade diagnostics.
• Multi-omics integration for spaceflight-stressor studies.
• Modeling cellular pathways, host-microbe interactions, and metabolic networks under spaceflight conditions.
• Computational simulation of closed-loop life support systems.
• Generative models for predictive simulation of astronaut physiology and disease states through Digital Twin Biology, including neural networks and deep learning.

Post Code 05

• Gait analysis, exercise countermeasure, motion capture and force-plate studies, and rehabilitation program development.
• Biomechanical analysis of the musculoskeletal system.
• Analyze human performance data from wearables.
• Collaborate on rodent/human analog design for spaceflight experiments.

Post Code 06

• Develop and validate bio-imaging systems for microgravity tissue changes. (marked "Strictly Confidential" in the original notification, reproduced as printed)
• Implement DSP algorithms for ECG/EEG/EMG from wearables; noise reduction and feature extraction.
• Analyze bioinformatics datasets for space radiation effects on cells/tissues.
• Development of portable diagnostic devices, biosensors, point-of-care testing, and real-time astronaut health monitoring tools.
• Integration of biomedical devices, wearable sensors, and lab-on-chip technologies.
• Integrate AI/ML for real-time signal/imaging analysis in human/rodent spaceflight experiments.

💰 Pay & Level in Pay Matrix

In addition to Basic Pay: Dearness Allowance (DA), House Rent Allowance (HRA), and Transport Allowance as per extant rules. Employees are governed by the National Pension System/Unified Pension Scheme. Additional benefits include medical facilities for self and dependents, subsidized canteen, quarters facility (in lieu of HRA), Leave Travel Concession, Group Insurance, and House Building Advance, per DOS/Central Government orders. HSFC also operates a periodic merit-based performance review system (Merit Promotion Scheme) for career advancement, de-linked from vacancy availability.

🎯 Selection Process

Based on the online application made on the ISRO Live Register portal, an initial screening will shortlist candidates directly for Personal Interview — there is no Recruitment Test or written examination in this process. The notification explicitly cautions that meeting the prescribed qualification is only the minimum requirement and does not automatically make a candidate eligible for interview/selection; final selection is based purely on interview performance. Candidates have the option to give the interview in Hindi.

📝 How to Apply

1. Visit the ISRO Live Register portal at https://www.isro.gov.in (under the "Career" tab).
2. Register afresh, or update your existing registration, on or before 30.08.2026, 5:00 PM.
3. Fill in all mandatory fields (marked *) accurately.
4. Upload the required photo, signature, and certificates as specified below.
5. Submit the application and note down your online Registration Number for future reference; also take a printout of the application.
6. Candidates registered under the National Career Service (NCS) portal and fulfilling eligibility conditions may also visit the ISRO website and follow this same procedure.

Note: Candidates can apply for more than one post, though HSFC reserves the right to conduct interviews for two or more posts simultaneously as per administrative exigency. Applications registered before 10.08.2026 or after 30.08.2026 will not be considered. No physical/postal applications will be entertained.

📤 Document Upload Guidelines

Applications with blurred, non-compliant, or incorrectly formatted images will be summarily rejected, as will applications submitted without complete information or without the requisite documents uploaded. Candidates should also be willing to undergo biometric verification if required.

📌 General Conditions (Applicable to All Posts)

• Only Indian Nationals are eligible to apply.
• Only online applications will be entertained; physical applications will not be considered.
• The posts are temporary, but likely to continue.
• The number of vacancies indicated is provisional and may be increased or decreased based on actual organizational requirements. ISRO/DOS/Centres/Autonomous Body reserves the right to cancel the recruitment at any stage.
• Canvassing in any form will be a disqualification.
• If any information furnished online is found incorrect at any stage of recruitment, the candidature will be cancelled.
• Candidates are liable to be posted at any Centre/Unit of ISRO or the Department of Space, anywhere in India.
• Any Addendum/Update/Corrigendum will be published only on the HSFC/ISRO websites — candidates should check regularly.
• All communication regarding the Personal Interview (including e-admit card intimation) will be sent only via email/HSFC website. Candidates must furnish a correct email ID and check it regularly; HSFC/ISRO is not responsible for non-receipt of email due to technical or other reasons.
• Serving Central/State Government, PSU, or Autonomous Body employees must submit a No Objection Certificate (NOC) from their employer at the time of Personal Interview; failure to do so means the candidate will not be permitted to appear, and TA will not be paid.
• Candidates must produce original documents proving the details in their online application at the time of Personal Interview for verification; failure to do so means they will not be permitted to appear, and TA will not be paid.
• Outstation candidates called for interview will be reimbursed Second Class Railway fare, or non-AC bus fare, or actual expense — whichever is least — by the shortest route, on production of proof of journey.
• Legal proceedings arising from this advertisement fall under the sole and exclusive jurisdiction of the Courts at Bengaluru.
• In case of any ambiguity/dispute in interpreting the Hindi/English text of this advertisement, HSFC's decision is final.
• Selected candidates will be intimated by email and must join on being found medically fit.
• No correspondence will be entertained with candidates not screened in for interview or not selected.
• PwBD candidates may apply for posts suitable to them even if not specifically reserved, and will be considered by the general standard of merit; a minimum 40% relevant disability is required for age-relaxation benefit, per the Rights of Persons with Disabilities Act, 2016.
• DOS/ISRO reserves the right not to fill any of the posts, if it so desires.
• Government strives for a gender-balanced workforce and encourages women candidates to apply.

📞 Contact Details

Note: queries whose answers are already available in the advertisement will not be answered by phone/email, and no interim correspondence or phone calls will be entertained.

❓ Frequently Asked Questions

Q1. Is there a written exam for this HSFC recruitment?
No. Selection is based purely on Personal Interview after an initial screening of online applications. There is no Recruitment Test or written exam stage.

Q2. Is there any application fee?
No. There is no application fee for any of the 6 posts (Post Codes 01–06).

Q3. Can I apply for more than one post code?
Yes, candidates can apply for more than one post, though HSFC may conduct interviews for two or more posts simultaneously depending on administrative need. For Post Codes 05 and 06 specifically, the notification advises applying only against the post code matching your exact essential/pre-requisite qualification, since the discipline names overlap.

Q4. What is the age limit?
35 years as on the crucial date, 30.08.2026, with age relaxation for serving Central Govt employees, PwBD candidates, and Ex-servicemen as per extant Government of India rules.

Q5. Where do I apply?
Only online, through the ISRO Live Register portal at isro.gov.in, under the Career tab. Physical/postal applications are not accepted.

Q6. Is the total vacancy count of 6 stated explicitly in the notification, or calculated?
The notification lists 1 (UR) vacancy against each of the 6 post codes individually; it does not separately state a grand total figure. The figure of 6 used in this post is the sum of those individual rows.

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